COCH anticorps

N° du produit ABIN5703508

Cet anticorps Lapin Polyclonal détecte spécifiquement COCH dans ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour COCH anticorps (ABIN5703508)

Antigène: COCH (Cochlin (COCH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COCH est non-conjugé

Application: ELISA

Détail du produit anti-COCH anticorps

Fonction: COCH antibody

Immunogène: coagulation factor C homolog, cochlin (Limulus polyphemus)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur COCH

Antigène: COCH (Cochlin (COCH))

Autre désignation: COCH

Sujet:

Synonyms: Cochlin|COCH-5B2|COCH|COCH5B2

Background: The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.

ID gène: 1690

UniProt: O43405

Pathways: Sensory Perception of Sound